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Molecular and biochemical mechanisms mainly included the increased oxidative stress through polyol pathway flux, the accumulation of advanced glycation end products, the hexosamine pathway, and the protein kinase C pathway
doi:10.1016/0191-8869(94)00132-c
Methods State-of-the-art analytical methods were used to compare physical and chemical stability, and impurity profiles of drug substances/products from different suppliers
Some people may lose a few pounds in the first week due to a reduced appetite or smaller portion sizes
Timelines vary based on lifestyle, goals, and consistency
Notes: Monitor subjects glucose levels to prevent hypoglycemia
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