Indications and Usage for Cyanocobalamin Cyanocobalamin is indicated for vitamin B 12deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see Drug Interactions), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue
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Patients typically feel the increased energy, mental clarity, and mood enhancement from each B12 injection for 5-15 days on average before it tapers off
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It is still investigational
Here are a few reasons for this: Proteolysis (protein digestion): Protein digestion is likely to be impaired in hypothyroidism, but tends to be accelerated in hyperthyroidism