For maternal care, insulin or metformin are typically used for glycemic control in women with type 2 diabetes or insulin resistance
Tesamorelin alone holds limited regulatory approval for specific indications, while Ipamorelin remains investigational
To me the biggest concern is that these companies appear to be promoting a lifelong duration of therapy, as evident by their zero attention to getting people off the drugs, without reverting back for both weight gain and risk of adverse outcomes
Lipid-associated TAMs (LA-TAMs) represent a third emerging subset with high expression of lipid uptake receptors, cholesterol efflux transporters, and PPAR-driven immunosuppressive programs (108)
These renal benefits independently contribute to cardiovascular risk reduction, though SGLT2 inhibitors remain foundational therapy for heart failure and CKD when appropriate
After, pharmacies, telehealth companies and other health care providers could manufacture copycat GLP-1 therapies