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PMID: 38738258
TRIUMPH-1 (NCT05929066), the Phase 3 registration trial for the obesity indication, reported topline results on May 21, 2026 : average weight loss of 28.3% at 80 weeks at the highest dose in 2,339 participants, versus 2.2% on placebo, and 30.3% at 104 weeks among participants with a BMI of 35 or above who continued in a pre-specified extension
Ipamorelins selectivity means the modern stack does not produce the cortisol or prolactin spikes that older secretagogues caused
If you must venture out midday, stay in shade and limit exertion
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