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Many people take these medicines, so it is important to study potential risks associated with them, he noted in a press release

Food and Drug Administration (FDA) has approved semaglutide (marketed as Wegovy) and Tirzepatide (marketed as Zepbound) specifically for chronic weight management in adults with obesity or overweight individuals with at least one weight-related comorbidity, such as high blood pressure, type 2 diabetes, or high cholesterol

While more research is needed, preliminary studies suggest this combination approach may address multiple factors contributing to midlife weight changes

Patients with chronic hyperglycemia may have a significant negative effect on bone mass

Following oral administration, peak effects typically occur within 15 hours