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Its GLP-1 receptor agonist portfolio, anchored by semaglutide in its injectable form (Ozempic for diabetes, Wegovy for obesity) and oral form (Rybelsus), generated approximately USD 26 billion in combined sales in 2024, making semaglutide the world's highest-revenue drug
(7) Diotallevi M, Checconi P, Palamara AT, Celestino I, Coppo L, Holmgren A, Abbas K, Peyrot F, Mengozzi M, Ghezzi P
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Because oral glutathione supplements have historically demonstrated poor bioavailability and are rapidly broken down by enzymes in the gastrointestinal tract, the body relies heavily on intracellular de novo synthesis to maintain its protective antioxidant pools
Its gastric stability is remarkable: it survives the stomach's pH of 1-2 without being degraded, opening the possibility of oral administration in certain preclinical protocols