In many cases, acute Lyme disease becomes chronic Lyme due to the involvement of co-infections, immune dysregulation, persister bacteria, biofilms, toxins, and cellular stress that complicate the treatment procedure and prolong the recovery time
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Phytomedicine-Based Potent Antioxidant, Fisetin Protects CNS-Insult LPS-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment
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However, retrospective, uncontrolled studies of this size cannot establish efficacy
doi: 10.3389/fendo.2026.1858420 Received 17 April 2026 Revised 19 June 2026 Accepted 19 June 2026 Published 06 July 2026 Volume 17 - 2026 Edited by Srinivas Mummidi, Texas A&M University San Antonio, United States Reviewed by Raylene A