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For context, 44% of Wegovy-treated participants experienced nausea, 30% diarrhea, and 24% constipation
Melanin is responsible for hyperpigmentation resulting in skin darkening
Tirzepatide builds on that by targeting two pathways, including GLP1 and glucose-dependent insulinotropic polypeptide (GIP) which can enhance its effect for some patients
GLP-1 patches represent an emerging transdermal delivery system for glucagon-like peptide-1 (GLP-1) receptor agonists, medications traditionally administered via subcutaneous injection
doi:10.1152/ajpgi.00261.2020
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