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This indicates that DPP-4i treatment is in some cases attempted before switch to GLP-1 RAs, as the cost of DPP-4is is lower, and GLP-1 RAs (during the period in which this study was conducted) required injections

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the injection has fewer timing rules

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Weight regain is very common after stopping a GLP-1on average, up to two-thirds of the lost weight is regained within one year