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doi: 10.1093/ajcn/72.1.257S 49
It delays stomach emptying, inhibits appetite by activating specific GLP-1 receptors, increases insulin production from pancreatic beta cells, and lowers glucagon secretion from alpha cells
For patients identifying as Asian, 73 reported not using GLP-1RA compared to one patient reported as using GLP-1RA, which resulted in a near-complete separation of data for this patient population
Whereas 66.5% of those taking semaglutide achieved weight reductions of at least 10%, the same was true for 15.5% taking the placebo
For individuals who are obese, semaglutide can be an effective weight loss aid