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On the contrary, administration of dynasore (inhibitor of VEGGR2) didnt activate the pathway and blocked endothelial tube formation [3]
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However, the net effect depends on overall biological context, regulatory mechanisms, and timing
These effects were associated with increased F-actin formation and activation of focal adhesion kinase (FAK) and paxillin phosphorylation, signaling events central to cell attachment and cytoskeletal remodeling during tissue repair processes [4]
Acknowledgements R
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