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10.1016/j.ejmech.2020.113123 88 NeefJ.PalaciosD

Safety and tolerability outcomes comprised discontinuation of treatment due to adverse events, incidence of serious adverse events, all-cause mortality, hypoglycaemia (plasma glucose 3.9 mmol/l), severe hypoglycaemia (a hypoglycaemic event requiring assistance), nausea, vomiting and diarrhoea

Neuroprotective Effects: LDN has shown potential in protecting against neurodegenerative diseases by reducing neuroinflammation and promoting healthy brain function

DNA substrates All DNA oligonucleotides used in the experiments were purchased purified from IDT (Table 1)

Data from cell culture experiments such as those by Maar et al