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doi: 10.1016/j.animal.2022.100600 40 MengY

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& Kobayashi, S

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Nonetheless, this classical view has been challenged by the development of thiazolidinediones, which possess potent insulin-sensitizing properties despite having very low to absent PPAR-binding affinity 51

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The addition of spironolactone as a fourth-line therapy has been shown to significantly improve blood pressure control, as demonstrated in the PATHWAY-2 trial

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