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In obesity-related KOA, adiposity may aggravate pain and disability through increased joint loading, low-grade inflammation, metabolic dysfunction, impaired physical activity, and reduced rehabilitation tolerance

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This phenomenon can be explained by several mechanisms related to its action in the body: Increased fat metabolism : Carnitine plays a key role in transporting fatty acids to the mitochondria of cells, where they are burned to produce energy

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9 g/day for 6 months raised mortality in a 153-patient post-infarction trial[16]L-Arginine in Post-MI VINTAGE Trial JAMA (2006) View source

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