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Depuis le 23 juin 2025, tout mdecin est autoris prescrire les analogues du GLP-1 selon les modalits prvues par lautorisation de mise sur le march (AMM)

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A clinical trial showed that with Wegovy, the major adverse cardiovascular events (heart attack, stroke, cardiovascular death) can be reduced by 20% in specific patients with heart disease

others do well with periodic use

Fibroblast growth factor 21 attenuates hypoxia-induced pulmonary hypertension by upregulating PPAR expression and suppressing inflammatory cytokine levels

In addition, other risk factors include obesity, pregnancy, chronic coughing, smoking, and heavy lifting