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Sublingual drops are better than oral tablets but the best way to know that you are getting the B-12 you need is to take it via injection
If youre switching to liraglutide (daily injections), your first dose can also be taken 7 days after your last weekly injection
1218 For instance, in the Small Changes and Lasting Effects (liraglutide) trial and SURMOUNT-1 (tirzepatide) trials, patients were excluded if they were taking medications that may contribute to weight gain including tricyclic antidepressants, mirtazapine, paroxetine, and several antidepressants and mood stabilizers
Only about 1% of the oral dose is absorbed, which is why Rybelsus requires such specific dosing conditions
10.1016/s0140-6736(87)91194-9 Lancet 21 KruitJ
The key difference is mechanism: semaglutide activates GLP-1 receptors only, while tirzepatide activates both GLP-1 and GIP receptors, a dual-action approach that appears to amplify appetite suppression and fat metabolism
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