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Dozens of wellness and direct-to-consumer telehealth companies offering GLP-1s have begun marketing cash-pay hormone replacement therapy to women in perimenopause and menopause, and testosterone replacement therapy to men
GLP-1RAs suppress the progression of atherosclerosis in ApoE -/- , LDLr -/- , and even in moderate uremia LDLr -/- mice[16, 60]
It is possible therefore that a poor gut biome, or indeed even the source of ALCAR/LC may be important in describing outcomes
Potential metabolic effects of allulose (requiring further research): Modest reduction in postprandial glucose levels Possible stimulation of endogenous GLP-1 secretion Potential improvement in insulin sensitivity Reduction in overall caloric intake when substituted for sugar Patients should discuss any dietary modifications with their healthcare provider, particularly when managing diabetes or taking glucose-lowering medications
It stimulates growth hormone release by acting on the ghrelin/growth hormone secretagogue receptor (GHS-R) without significantly affecting cortisol, prolactin, or ACTH levels
Allan C
