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(2025) 17:e86080

Toxicity assessment of copper oxide nanoparticles: in vivo study

S., Ramachandran, V., van Lent, D

doi:10.1210/endrev/bnac003

In vitro, KYNA protects cortical neurons from reactive glia- and QA-induced atrophy, enhancing neurite complexity and synapse formation, indicating that increasing KYNA or inhibiting glial KP activity can mitigate excitotoxic and inflammatory neuronal damage [86]