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GHRH analogues act at the GHRH receptor on pituitary somatotropes
Tirzepatide was removed from the FDA shortage list, and the compounding exemptions that allowed routine production of tirzepatide copies have largely expired
They need a different tool
In between-drug comparisons, tirzepatide at both the 15 mg and 10 mg doses outperformed all doses of semaglutide, while tirzepatide at the 5 mg dose was more efficacious than semaglutide 0.5 mg (ESM Table 13)
Mestre H, Hablitz LM, Xavier AL, Feng W, Zou W, Pu T, et al
10.1016/j.febslet.2008.05.021 383
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