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DOI: 10.1002/pro.5560060507 34
Although APAP-induced liver injury (AILI) is thought to be associated with direct hepatotoxicity of APAP, recent evidence suggests that intestinal events, such as gut microbiota dysbiosis, impaired barrier function, and activation of inflammatory or metabolic pathways, play an important role in the process of AILI [4]
No validated injectable dose and no human trial
Melanocytopenic hypomelanosis is characterized by reduced or absent vs a reduction in the number of melanocytes, whereas melanopenic hypomelanosis features a normal number of melanocytes but decreased melanin synthesis or transfer to keratinocytes
10.1111/j.1360-0443.2004.00879.x 87 NguyenT
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