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Heme oxygenase-1 inhibits T cell-dependent skin inflammation and differentiation and function of antigen-presenting cells
MSM contained, per litre: 1 g of NaCl, 1.5 g of K 2 HPO 4 , 0.75 g of KH 2 PO 4 , 1 g of NH 4 NO 3 and 0.2 g of MgCl 2
Causes of Melasma: Hormonal fluctuations (pregnancy, birth control pills, hormone therapy) UV radiation exposure Genetic predisposition Heat and infrared light Appearance of Melasma: Symmetrical patches on the cheeks, forehead, nose bridge, or upper lip Larger, diffused patches rather than sharp dark spots Worsens with sun exposure What is Post-Inflammatory Hyperpigmentation (PIH)