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It aimed at assessing glycyrrhizin as an active component of the licorice root Flavonoids on the elimination of CP-associated side effects in fifty-four male adult Sprague Dawley

Abbreviations BBB: Bloodbrain barrier CFS: Chronic fatigue syndrome CNS: Central nervous system CoA: Coenzyme A COVID-19: Coronavirus disease 2019 CrAT: Carnitine acetyltransferase CRP: C-reactive protein HPA: Hypothalamicpituitaryadrenal IDO: Indoleamine 2,3-dioxygenase IL-2: Interleukin-2 IMD: Immunometabolic depression MDD: Major depressive disorder ME: Myalgic encephalomyelitis mGluR2: Metabotropic glutamate receptor 2 MS: Multiple sclerosis NMDA: N -Methyl-d-aspartate NMR: Nuclear magnetic resonance Nrf2: Nuclear factor erythroid 2-related factor 2 OCTN2: Organic cation novel type 2 transporter OCT1: Organic cation transporter 1 PAIS: Post-acute infection syndromes PASC: Post-acute sequelae of SARS-CoV-2 infection PDC: Pyruvate dehydrogenase complex PGD2S: Prostaglandin D2 synthase gene QUIN: Quinolinic acid ROS: Reactive oxygen species Trp: Tryptophan TCA: Tricarboxylic acid HO-1: Heme oxygenase 1 PUFAs: Polyunsaturated fatty acids CACT: Carnitine-acylcarnitine translocase MRI: Magnetic resonance imaging [ 18 F]FDG-PET/CT: [ 18 F]Fluorodeoxyglucose positron emission tomography/computed tomography References Abraham NG, Kappas A (2008) Pharmacological and clinical aspects of heme oxygenase

In response, the body repairs and rebuilds those fibers, making them stronger and larger over time

Spooner LM, Olin JL

Low glutathione levels could contribute to common symptoms, including fatigue, pain, brain fog, poor sleep, low immunity, and other adverse health conditions

Chavoshi Nezhad N et al