retatrutide phase 2 nejm 2023 obesity trial results For patients with #obesity, semaglutide, a glucagon-like peptide-1 receptor agonist, is approved for weight management as a once-weekly subcutaneous injection. In a previous trial, oral semaglutide at a dose of 50 mg Retatrutide vs Wegovy: which works

States continue to consider PBM reform

A nationwide cohort study from Sweden and Denmark found no significant increase in suicide deaths among GLP-1 RA users compared to Sodium-glucose cotransporter-2 (SGLT2) inhibitors, and even reported a lower incidence of combined suicide and self-harm outcomes (HR 0.83) [47]

CrossRef 11,788 View 433 Download 11 Web of Science Crossref Normal-weight metabolic dysfunction-associated steatotic liver disease: reclassification, characteristics, and adverse liver outcomes across diverse populations Sherlot Juan Song, Eileen Laureal Yoon, Vincent Wai-Sun Wong, Ae Jeong Jo, Grace Lai-Hung Wong, Jimmy Che-To Lai, Dae Won Jun, Terry Cheuk-Fung Yip Clin Mol Hepatol 2026;32(2):646-660

Periodic check-ins are completed online, and the care team can adjust dosage or modify the treatment plan based on those interactions without requiring a separate appointment

[2] Dulaglutide (Trulicity), another once-weekly injectable GLP-1 agonist, demonstrates a somewhat more favourable gastrointestinal tolerability profile in some studies, with nausea reported in approximately 8-12% of patients at lower doses, though rates increase with higher doses (3

Tanofsky-Kraff et al., 2008