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Differentiation and culturing of neural progenitor cell WA09 (H9) human ESCs were maintained on matrigel-coated plates in E8 media 43 (all media and components are listed in Supplementary Tables 3 and 4)

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10.1007/s00395-015-0476-7 65 RochoJ.KalinowskiP.Szymanek-MajchrzakK.GrtM

1,6 While specific data vary by product and region, the general expectation is: Mid-2020s - early 2030s: foundational peptide patents expire Late 2020s - mid-2030s: formulation and device patents phase out Ongoing regulatory exclusivities (e.g., data exclusivity) may further delay competition