Liu, L., Chen, J., Wang, L., Chen, C
Spatial and temporal precision in delivery and regulation Jia et al (185) demonstrated that adeno-associated virus-mediated Trx1 overexpression restricted to the hippocampus in APP/PS1 mice improved cognitive function without disrupting systemic redox homeostasis
Real-World Clinical Experience of Semaglutide in Secondary Care Diabetes: A Retrospective Observational Stud
The same paper also included a nested case-control component of 120,054 patients with T2DM followed for 7.4 years and observed a lower association between dementia and exposure to GLP-1RAs compared with other antidiabetics 39
It may be one of the first peptides shown to act as a selective gene expression modulator, without the off-target chaos of pharmacological epigenetic drugs
Research has shown that people who are prescribed phentermine long-term to treat obesity dont develop a craving for the drug (12)