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4.3 Modulation of SCFAs-producing bacteria by metformin SCFAs (such as acetic acid, propionic acid and butyric acid) are usually metabolites produced by various SCFAs-producing bacteria in the gut that metabolizes carbohydrates such as dietary fiber (Rau et al., 2018), and they are essential for the health of the gut, the body and even the brain
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Key ClinicalTrials.gov Numbers for Reference TRIUMPH-1 (main obesity): NCT05929066 TRIUMPH-2 (obesity + T2 diabetes): NCT05929079 TRIUMPH-3 (obesity + CV disease): NCT05882045 TRIUMPH-4 (obesity + knee OA): NCT05931367 TRIUMPH-Outcomes (CV + renal outcomes): NCT06383390 Source: ClinicalTrials.gov
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whether the delivery format supports probiotic viability
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