EA reduces OGD/R-induced ferroptosis in hippocampal neurons
Liu W, Zhou W, Zhao P, Wu T, Gu H, Li Y, Zhong C, Bai H, Zhao N, Huang X (2025) PD-Like pathogenesis in Caenorhabditis elegans intestinally infected with Nocardia farcinica and the underlying molecular mechanisms
they create what researchers refer to as a massive immunological "energy sink." Because the immune cells (particularly T-cells and memory lymphocytes) are trapped in a state of severe oxidative stress, they are forced to consume excessive amounts of the host's energy just to survive the ongoing cellular damage and attempt repairs
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Pharmaceuticals (Basel, Switzerland) , 17 (4)
Additionally, the mutant huntingtin protein can impair the function of the transcription factor PGC-1, which is crucial for the regulation of antioxidant defenses and mitochondrial biogenesis