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Amylin analogs are challenging to manufacture because amylin is notoriously aggregation-prone, requiring specific amino-acid substitutions and synthesis controls
Doxorubicin induces the persistent activation of intracellular transglutaminase 2 that protects from cell death
Additional information Supplementary Information accompanies the paper on the Oncogene website Supplementary information Rights and permissions About this article Cite this article Dulak, A., Gubish, C., Stabile, L
Each format has tradeoffs that map onto where the user is in the staged titration protocol
Mild side effects, such as minor bruising at the infusion site, are rare
Oxidative stress and its role in cancer
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