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This age-related decline corresponds with observable decreases in skin elasticity, wound healing capacity, and tissue regeneration
Regul Toxicol Pharmacol
The position this article takes, given those three valid critiques, is that the mechanism evidence is strong enough, the delivery evidence is biologically plausible enough, and the safety window is wide enough that the recommendation is defensible
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Stage 4 is REM sleep, associated with dreaming and cognitive processing
doi:10.1038/s41467-025-60844-9
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