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Nuclear Receptor Coactivator 4 ( NCOA4 ) functions as a selective autophagy adaptor that promotes ferritin autophagy degradation and induces cell ferroptosis 39
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their wild-type Gipr fl/fl littermates were used as controls for all experiments
The 1st glutathione-interaction site should be frequently (although transiently) occupied by GSH at millimolar concentrations, whereas diverse non-glutathione disulfide substrates are far less abundant in vivo and should encounter the active site less frequently
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