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However, in the non-Asian population, a double dose of liraglutide (1.8 mg) did not exhibit similar efficacy to 14 mg oral semaglutide (WMD: 0.3, P = 0.0005)
Annals of the NY Academy of Sciences , 1194, 179189
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While long-term studies in children are ongoing, 2026 clinical data shows promising results for safely managing adolescent obesity
Most regain the lost weight
Moreover, GLP-1 does not affect energy expenditure in humans [28] which means that this treatment does not compensate for the reduction in energy expenditure that is observed with weight loss, a phenomenon that again limits the weight loss associated with GLP-1 analogue treatment
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