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12 Replacement of GLP-1 His 7 with Phe 7 does not influence either its receptor affinity or cAMP activity, indicating that the aromaticity of His is crucial to its activity

Out of the 32 patients with symptomatic complicated gallstone, 9 (28.1%) were on liraglutide, 9 (28.1%) were on semaglutide, 7 (21.9%) were on dulaglutide, and 7 (21.9%) were not on GLP-1RAs