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PhGs show significant hepatoprotective potential through their multi-target mechanisms, addressing critical processes such as oxidative stress, inflammation, apoptosis, and fibrosis

Methods A previously developed, two-compartment pharmacokinetic model, based on subcutaneous and intravenous semaglutide, was extended to include data from six oral semaglutide trials conducted in either healthy volunteers or subjects with renal or hepatic impairment

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GIPR antagonist antibodies conjugated to GLP-1 peptide are bispecific molecules that decrease weight in obese mice and monkeys

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