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A Study of Sirt1 Regulation and the Effect of Resveratrol on Synoviocyte Invasion and Associated Joint Destruction in Rheumatoid Arthritis
10.1016/j.intimp.2009.06.001 Int Immunopharmacol
Ge et al., 2022)
Results: We confirmed the canonical inflammasome pathway in MCD-induced NASH mice by detecting the increased protein levels of NLRP3, GSDMD, GSDMD-N, Caspase-1, and Caspase-1 P20 in NASH mice
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A 2022 study in Diabetes, Obesity and Metabolism showed that NNMTi treatment combined with reduced-calorie diet "promoted dramatic whole-body adiposity and weight loss in diet-induced obese mice, rapidly normalizing" weight parameters
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