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To optimize KAI-7535s overall clinical profile for the treatment of obesity in diverse patient populations, we are assessing a wide dose range, a lower starting dose, and a more gradual titration in our ongoing Phase 2 global clinical trial, Kailera Chief Medical Officer Scott Wasserman said in a prepared statement
Clinical trial of leptin replacement therapy The first genetic evidence of congenital leptin deficiencies in humans with severe obesity emerged in 1997 (Montague et al., 1997)
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van Mierlo LA, Arends LR, Streppel MT, et al
Your stomach empties more slowly, food stays in your stomach longer, and your brain receives stronger fullness signalsall of which can feel like mild to moderate nausea, especially when you eat quickly or consume larger meals
