Notably, a clinical study demonstrated that T2DM patients receiving insulin therapy experienced significantly higher rates of pancreatitis compared to those treated with GLP-1RAs, and notably, no pancreatitis cases have been reported in clinical trials of the novel GLP-1RA Cotadutide, indicating that a comprehensive risk assessment of GLP-1RAs for pancreatic cancer remains premature pending additional data on these novel medications [8]
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N Engl J Med 390(15):13941407 Petrie MC, Borlaug BA, Butler J, Davies MJ, Kitzman DW, Shah SJ et al (2024) Semaglutide and NT-proBNP in obesity-related HFpEF
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Role of leptin and adiponectin in immune response and inflammation