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Results vary, and treatment should only be considered under medical supervision

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Same medication category, different purpose, different outcome

Balogun E et al

P53 phosphorylation at Ser15 was confirmed to enhance the affinity for both FOXO4 and FOXO4-DRI, providing a structural explanation for FOXO4-DRIs preferential engagement with the hyperphosphorylated p53 that characterises senescent cells