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In their separate Phase 2 trials, retatrutide monotherapy showed larger weight loss (~24.2% at 48 weeks, 12 mg) than standalone cagrilintide (~10.8% at 26 weeks, 4.5 mg), and indirect network meta-analyses rank retatrutide highly
Room temperature storage destroys them within 24 hours
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Patients with Normal Intestinal Absorption: Where the oral route is not deemed adequate, initial treatment similar to that for patients with pernicious anemia may be indicated depending on the severity of the deficiency
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