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Specifically, HFDs contribute to lipid accumulation in non-adipose ovarian cells, promote lipotoxicity, induce chronic low-grade inflammation, and elevate ROS, ultimately disrupting oocyte development and fertility outcomes (Di Berardino et al., 2024
Not all individuals will qualify for medication-based treatment
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Physical exercise has been shown to independently modulate oxylipin profiles, promoting a shift toward anti-inflammatory and pro-resolving metabolites that support mitochondrial biogenesis, angiogenesis, and muscle protein synthesis
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