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In its Complete Response Letter on Tuesday, the FDA indicated that it was continuing to review safety data for Ocaliva from one of its confirmatory studies
2010;86(Suppl 1):135
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se in alcuni stato evidenziato un ridotto rischio di aritmie e angina (ma non di insufficienza cardiaca e infarto), altri hanno evidenziato addirittura un possibile aumento del rischio di sviluppare malattie cardiache
These groups include vegetarians, vegans, and persons with pernicious anemia, gastrointestinal disorders and alcohol abuse problems
Delayed gastric emptying can increase intragastric pressure and potentially promote gastroesophageal reflux, particularly in patients with pre-existing GERD or those who overeat despite reduced appetite signals
It is crucial to understand the regulatory status of these options
