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What types of experimental models are commonly used with DSIP
PO phenytoin has ~90% bioavailability, so a 1:1 conversion is often used to convert between PO and IV administration
Presented for research literature review only Paterna S et al
Upregulated DGKH activates the mTOR signaling pathway by enhancing PA synthesis, thereby promoting HCC metastasis, stemness, and drug resistance [213]
Additional information Competing interests The authors declare that they have no competing interests Authors' contributions NSG wrote the manuscript and performed the experiments and analyzed the samples
This is a reversible modification and adding sodium borohydride (NaBH4) results in the GSH release, which can subsequently react with DTNB and be measured
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