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Retrieved 2009-07-23
As there is no meaningful expression of GLP-1 receptors on hepatocytes, the major effect of GLP-1 agonists on MASH is likely to be indirect and may be related to a reduction in calorie intake, body weight and insulin resistance, all of which would lead to reduced liver lipid accumulation and hepatic inflammation 7,8
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C., Baade, P
Most infusions run about 60 minutes
Beyond these clinically recognized effects, sustained caloric restriction during pharmacological weight reduction represents a chronic constraint on systemic energy flux
