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However, we are also beginning to learn of adverse effects, including pancreatitis, renal dysfunction, gastroparesis, and serious anesthesia complications, leading the American Society of Anesthesiologists (ASA) to release new guidance for perioperative management of these medications

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Additionally, a meta-analysis of 46 randomized trials, including 171,244 participants, found that supplemental vitamin E, singly or in combination with other antioxidants, did not significantly alter the risk of all-cause mortality (126)

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