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2.3.2 Gut microbiota and its metabolites modulate GLP-1 secretion Emerging evidence highlights a bidirectional regulatory interplay between the gut microbiota and GLP-1, whereby microbial composition and metabolites exert profound influences on GLP-1 synthesis, secretion, and signaling

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21 It has been shown to be effective in long-term weight management and reducing the risk for chronic diseases such as heart disease, type 2 diabetes, and cancer