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What I want patients and clinicians to take away from this is that if you or your patient has obesity, established cardiovascular disease, type 2 diabetes, CKD, HFpEF, MASH, or sleep apnea, this drug class should be a serious part of the treatment conversation

Is Melanotan 2 Right for You

Long-term dosing considerations Both compounds are intended for long-term use

With its approximate 5-day half-life and once-weekly dosing schedule, the medication achieves steady-state plasma levels after approximately four to five weeks of consistent administration at a given dose

Most patients (97%) were treated with one or more glucose lowering medications at baseline: metformin (76%), insulin (51%), SGLT-2 inhibitor (27%), sulfonylurea (29%), and DPP-4 inhibitor (23%)

Keep a dated record of symptoms, treatments, and missed workdays