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Originally investigated for its potential to combat obesity, metabolic syndrome, and age-related decline, this NNMT (nicotinamide N-methyltransferase) inhibitor has shown promise in boosting fat metabolism, preserving lean muscle mass, and increasing energy efficiency

The addition of lipoic acid further increased improvements in both clinical symptoms and NCV

The trade-off is twice as many injections and slightly more complex scheduling

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Regular monitoring of B12 levels is crucial and healthcare providers can order periodic blood tests to track B12 levels, tailored to individual risk factors and health conditions

While some individuals may require weekly injections initially to address severe deficiency, the frequency often decreases over time as B12 levels stabilize