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In addition, by screening differentially expressed genes (such as endothelial NOS and inflammatory factors) through transcriptomics, validating key proteins (such as VEGF and ICAM-1) through proteomics, and analyzing small molecule metabolites (such as NO and oxidative stress markers) through metabolomics, a molecular network of endothelial injury can be jointly constructed [33]
Where most therapeutic peptides degrade within minutes under simulated gastric or intestinal conditions, BPC-157 retains its integrity in human gastric juice for more than 24 hours, tolerates a wide pH range, and resists multiple proteolytic enzymes including pepsin and trypsin
Liu T, Deng K, Xue Y, Yang R, Yang R, Gong Z, et al
