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The American Academy of Pediatrics and several international organizations recommend prophylactic IM injection of vitamin K 1 within six hours of birth for the prevention of VKDB

In comparison, 634 patients with PCOS who continued metformin treatment during early pregnancy exhibited a birth defect rate of 0.5% (Newman and Dunne, 2022)

45 Additional studies confirmed that N-AcGIP, another long-acting GIP agonist, 46 decreased osteoclast-mediated bone resorption and enhanced cortical bone quality in rodents

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Thus, inhibition of LOXL2 by an anti-LOXL2 monoclonal antibody may lead to a reduction in fibrosis