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This results in persistent hunger despite sufficient or excess energy intake (5)
Fish disease and intestinal microbiota: A close and indivisible relationship
In contrast, GLP-1sincluding semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro, Zepbound)represent a significant departure from previous treatment paradigms.[127] By mimicking natural satiety signals and regulating appetite through the gut-brain axis, these medications offer a new kind of intervention that can address core drivers of obesity.[128] Clinical trials have demonstrated average weight loss of 15 percent, comparable to outcomes previously only achievable through bariatric surgery.[129] This level of efficacy, combined with growing demand, marks a potential inflection point in how obesity is treated
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This localized neuroinflammation and metabolic starvation in the brain are primary drivers of the severe cognitive impairment, or "brain fog," that plagues so many long-haulers
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