Compounded semaglutide is different because it is not FDA-approved and does not go through the same premarket review
The reaction involves mast cell degranulation and histamine release at the injection depot, producing the classic inflammatory triad: redness (vasodilation), swelling (plasma extravasation), and pain (nociceptor activation)
Once the medication is stopped, many patients experience significant weight regain unless they have made permanent lifestyle changes to support their results
Information for Patients Patients with pernicious anemia should be informed that they will require monthly injections of vitamin B 12for the remainder of their lives

Indications and Usage Ozempic (semaglutide) injection 0.5 mg, 1 mg, or 2 mg and Ozempic (semaglutide) tablets 4 mg or 9 mg are indicated: as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes Ozempic injection is indicated: to reduce the risk of major adverse cardiovascular (CV) events (CV death, nonfatal myocardial infarction, or nonfatal stroke) in adults with type 2 diabetes and established CV disease to reduce the risk of sustained eGFR decline, end-stage kidney disease, and cardiovascular death in adults with type 2 diabetes and chronic kidney disease Ozempic tablets are indicated: to reduce the risk of major adverse cardiovascular (CV) events (CV death, nonfatal myocardial infarction, or nonfatal stroke) in adults with type 2 diabetes who are at high risk for these events Important Safety Information for Ozempic WARNING: RISK OF THYROID C-CELL TUMORS In rodents, semaglutide causes dose-dependent and treatment-duration- dependent thyroid C-cell tumors at clinically relevant exposures

Your body cannot process double the GLP-1 receptor activation safely, and the side effects will be disproportionately worse than any benefit from the extra semaglutide